Furan-Ofteno
Brand names,
Furan-Ofteno
Analogs
Furan-Ofteno
Brand Names Mixture
Furan-Ofteno
Chemical_Formula
C6H6N4O4
Furan-Ofteno
RX_link
No information avaliable
Furan-Ofteno
fda sheet
Furan-Ofteno
msds (material safety sheet)
Furan-Ofteno
Synthesis Reference
No information avaliable
Furan-Ofteno
Molecular Weight
198.136 g/mol
Furan-Ofteno
Melting Point
238 oC
Furan-Ofteno
H2O Solubility
210 mg/L (Approximately 50%)
Furan-Ofteno
State
Solid
Furan-Ofteno
LogP
0.517
Furan-Ofteno
Dosage Forms
Ointment
Furan-Ofteno
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furan-Ofteno
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furan-Ofteno
Absorption
Well absorbed.
Furan-Ofteno
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furan-Ofteno
Patient Information
No information avaliable
Furan-Ofteno
Organisms Affected
Gram negative and gram positive bacteria