Dermofural
Brand names,
Dermofural
Analogs
Dermofural
Brand Names Mixture
Dermofural
Chemical_Formula
C6H6N4O4
Dermofural
RX_link
No information avaliable
Dermofural
fda sheet
Dermofural
msds (material safety sheet)
Dermofural
Synthesis Reference
No information avaliable
Dermofural
Molecular Weight
198.136 g/mol
Dermofural
Melting Point
238 oC
Dermofural
H2O Solubility
210 mg/L (Approximately 50%)
Dermofural
State
Solid
Dermofural
LogP
0.517
Dermofural
Dosage Forms
Ointment
Dermofural
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Dermofural
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Dermofural
Absorption
Well absorbed.
Dermofural
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Dermofural
Patient Information
No information avaliable
Dermofural
Organisms Affected
Gram negative and gram positive bacteria