Nfz Mix
Brand names,
Nfz Mix
Analogs
Nfz Mix
Brand Names Mixture
Nfz Mix
Chemical_Formula
C6H6N4O4
Nfz Mix
RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
Nfz Mix
Molecular Weight
198.136 g/mol
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Melting Point
238 oC
Nfz Mix
H2O Solubility
210 mg/L (Approximately 50%)
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State
Solid
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LogP
0.517
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Dosage Forms
Ointment
Nfz Mix
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nfz Mix
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nfz Mix
Absorption
Well absorbed.
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side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
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Patient Information
No information avaliable
Nfz Mix
Organisms Affected
Gram negative and gram positive bacteria