Dymazone
Brand names,
Dymazone
Analogs
Dymazone
Brand Names Mixture
Dymazone
Chemical_Formula
C6H6N4O4
Dymazone
RX_link
No information avaliable
Dymazone
fda sheet
Dymazone
msds (material safety sheet)
Dymazone
Synthesis Reference
No information avaliable
Dymazone
Molecular Weight
198.136 g/mol
Dymazone
Melting Point
238 oC
Dymazone
H2O Solubility
210 mg/L (Approximately 50%)
Dymazone
State
Solid
Dymazone
LogP
0.517
Dymazone
Dosage Forms
Ointment
Dymazone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Dymazone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Dymazone
Absorption
Well absorbed.
Dymazone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Dymazone
Patient Information
No information avaliable
Dymazone
Organisms Affected
Gram negative and gram positive bacteria