Cocafurin
Brand names,
Cocafurin
Analogs
Cocafurin
Brand Names Mixture
Cocafurin
Chemical_Formula
C6H6N4O4
Cocafurin
RX_link
No information avaliable
Cocafurin
fda sheet
Cocafurin
msds (material safety sheet)
Cocafurin
Synthesis Reference
No information avaliable
Cocafurin
Molecular Weight
198.136 g/mol
Cocafurin
Melting Point
238 oC
Cocafurin
H2O Solubility
210 mg/L (Approximately 50%)
Cocafurin
State
Solid
Cocafurin
LogP
0.517
Cocafurin
Dosage Forms
Ointment
Cocafurin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Cocafurin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Cocafurin
Absorption
Well absorbed.
Cocafurin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Cocafurin
Patient Information
No information avaliable
Cocafurin
Organisms Affected
Gram negative and gram positive bacteria