Nitrofurazan
Brand names,
Nitrofurazan
Analogs
Nitrofurazan
Brand Names Mixture
Nitrofurazan
Chemical_Formula
C6H6N4O4
Nitrofurazan
RX_link
No information avaliable
Nitrofurazan
fda sheet
Nitrofurazan
msds (material safety sheet)
Nitrofurazan
Synthesis Reference
No information avaliable
Nitrofurazan
Molecular Weight
198.136 g/mol
Nitrofurazan
Melting Point
238 oC
Nitrofurazan
H2O Solubility
210 mg/L (Approximately 50%)
Nitrofurazan
State
Solid
Nitrofurazan
LogP
0.517
Nitrofurazan
Dosage Forms
Ointment
Nitrofurazan
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrofurazan
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrofurazan
Absorption
Well absorbed.
Nitrofurazan
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrofurazan
Patient Information
No information avaliable
Nitrofurazan
Organisms Affected
Gram negative and gram positive bacteria