Yatrocin
Brand names,
Yatrocin
Analogs
Yatrocin
Brand Names Mixture
Yatrocin
Chemical_Formula
C6H6N4O4
Yatrocin
RX_link
No information avaliable
Yatrocin
fda sheet
Yatrocin
msds (material safety sheet)
Yatrocin
Synthesis Reference
No information avaliable
Yatrocin
Molecular Weight
198.136 g/mol
Yatrocin
Melting Point
238 oC
Yatrocin
H2O Solubility
210 mg/L (Approximately 50%)
Yatrocin
State
Solid
Yatrocin
LogP
0.517
Yatrocin
Dosage Forms
Ointment
Yatrocin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Yatrocin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Yatrocin
Absorption
Well absorbed.
Yatrocin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Yatrocin
Patient Information
No information avaliable
Yatrocin
Organisms Affected
Gram negative and gram positive bacteria