Furalone
Brand names,
Furalone
Analogs
Furalone
Brand Names Mixture
Furalone
Chemical_Formula
C6H6N4O4
Furalone
RX_link
No information avaliable
Furalone
fda sheet
Furalone
msds (material safety sheet)
Furalone
Synthesis Reference
No information avaliable
Furalone
Molecular Weight
198.136 g/mol
Furalone
Melting Point
238 oC
Furalone
H2O Solubility
210 mg/L (Approximately 50%)
Furalone
State
Solid
Furalone
LogP
0.517
Furalone
Dosage Forms
Ointment
Furalone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furalone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furalone
Absorption
Well absorbed.
Furalone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furalone
Patient Information
No information avaliable
Furalone
Organisms Affected
Gram negative and gram positive bacteria