Furatsilin
Brand names,
Furatsilin
Analogs
Furatsilin
Brand Names Mixture
Furatsilin
Chemical_Formula
C6H6N4O4
Furatsilin
RX_link
No information avaliable
Furatsilin
fda sheet
Furatsilin
msds (material safety sheet)
Furatsilin
Synthesis Reference
No information avaliable
Furatsilin
Molecular Weight
198.136 g/mol
Furatsilin
Melting Point
238 oC
Furatsilin
H2O Solubility
210 mg/L (Approximately 50%)
Furatsilin
State
Solid
Furatsilin
LogP
0.517
Furatsilin
Dosage Forms
Ointment
Furatsilin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furatsilin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furatsilin
Absorption
Well absorbed.
Furatsilin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furatsilin
Patient Information
No information avaliable
Furatsilin
Organisms Affected
Gram negative and gram positive bacteria