Furacillin
Brand names,
Furacillin
Analogs
Furacillin
Brand Names Mixture
Furacillin
Chemical_Formula
C6H6N4O4
Furacillin
RX_link
No information avaliable
Furacillin
fda sheet
Furacillin
msds (material safety sheet)
Furacillin
Synthesis Reference
No information avaliable
Furacillin
Molecular Weight
198.136 g/mol
Furacillin
Melting Point
238 oC
Furacillin
H2O Solubility
210 mg/L (Approximately 50%)
Furacillin
State
Solid
Furacillin
LogP
0.517
Furacillin
Dosage Forms
Ointment
Furacillin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furacillin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furacillin
Absorption
Well absorbed.
Furacillin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furacillin
Patient Information
No information avaliable
Furacillin
Organisms Affected
Gram negative and gram positive bacteria