Fedacin
Brand names,
Fedacin
Analogs
Fedacin
Brand Names Mixture
Fedacin
Chemical_Formula
C6H6N4O4
Fedacin
RX_link
No information avaliable
Fedacin
fda sheet
Fedacin
msds (material safety sheet)
Fedacin
Synthesis Reference
No information avaliable
Fedacin
Molecular Weight
198.136 g/mol
Fedacin
Melting Point
238 oC
Fedacin
H2O Solubility
210 mg/L (Approximately 50%)
Fedacin
State
Solid
Fedacin
LogP
0.517
Fedacin
Dosage Forms
Ointment
Fedacin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Fedacin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Fedacin
Absorption
Well absorbed.
Fedacin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Fedacin
Patient Information
No information avaliable
Fedacin
Organisms Affected
Gram negative and gram positive bacteria