Alfucin
Brand names,
Alfucin
Analogs
Alfucin
Brand Names Mixture
Alfucin
Chemical_Formula
C6H6N4O4
Alfucin
RX_link
No information avaliable
Alfucin
fda sheet
Alfucin
msds (material safety sheet)
Alfucin
Synthesis Reference
No information avaliable
Alfucin
Molecular Weight
198.136 g/mol
Alfucin
Melting Point
238 oC
Alfucin
H2O Solubility
210 mg/L (Approximately 50%)
Alfucin
State
Solid
Alfucin
LogP
0.517
Alfucin
Dosage Forms
Ointment
Alfucin
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Alfucin
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Alfucin
Absorption
Well absorbed.
Alfucin
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Alfucin
Patient Information
No information avaliable
Alfucin
Organisms Affected
Gram negative and gram positive bacteria