Nifuzon
Brand names,
Nifuzon
Analogs
Nifuzon
Brand Names Mixture
Nifuzon
Chemical_Formula
C6H6N4O4
Nifuzon
RX_link
No information avaliable
Nifuzon
fda sheet
Nifuzon
msds (material safety sheet)
Nifuzon
Synthesis Reference
No information avaliable
Nifuzon
Molecular Weight
198.136 g/mol
Nifuzon
Melting Point
238 oC
Nifuzon
H2O Solubility
210 mg/L (Approximately 50%)
Nifuzon
State
Solid
Nifuzon
LogP
0.517
Nifuzon
Dosage Forms
Ointment
Nifuzon
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nifuzon
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nifuzon
Absorption
Well absorbed.
Nifuzon
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nifuzon
Patient Information
No information avaliable
Nifuzon
Organisms Affected
Gram negative and gram positive bacteria