Nitrofurazone
Brand names,
Nitrofurazone
Analogs
Nitrofurazone
Brand Names Mixture
Nitrofurazone
Chemical_Formula
C6H6N4O4
Nitrofurazone
RX_link
No information avaliable
Nitrofurazone
fda sheet
Nitrofurazone
msds (material safety sheet)
Nitrofurazone
Synthesis Reference
No information avaliable
Nitrofurazone
Molecular Weight
198.136 g/mol
Nitrofurazone
Melting Point
238 oC
Nitrofurazone
H2O Solubility
210 mg/L (Approximately 50%)
Nitrofurazone
State
Solid
Nitrofurazone
LogP
0.517
Nitrofurazone
Dosage Forms
Ointment
Nitrofurazone
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Nitrofurazone
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Nitrofurazone
Absorption
Well absorbed.
Nitrofurazone
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Nitrofurazone
Patient Information
No information avaliable
Nitrofurazone
Organisms Affected
Gram negative and gram positive bacteria