Furose
Brand names,
Furose
Analogs
Furose
Brand Names Mixture
Furose
Chemical_Formula
C6H6N4O4
Furose
RX_link
No information avaliable
Furose
fda sheet
Furose
msds (material safety sheet)
Furose
Synthesis Reference
No information avaliable
Furose
Molecular Weight
198.136 g/mol
Furose
Melting Point
238 oC
Furose
H2O Solubility
210 mg/L (Approximately 50%)
Furose
State
Solid
Furose
LogP
0.517
Furose
Dosage Forms
Ointment
Furose
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furose
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furose
Absorption
Well absorbed.
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side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furose
Patient Information
No information avaliable
Furose
Organisms Affected
Gram negative and gram positive bacteria