Furazon
Brand names,
Furazon
Analogs
Furazon
Brand Names Mixture
Furazon
Chemical_Formula
C6H6N4O4
Furazon
RX_link
No information avaliable
Furazon
fda sheet
Furazon
msds (material safety sheet)
Furazon
Synthesis Reference
No information avaliable
Furazon
Molecular Weight
198.136 g/mol
Furazon
Melting Point
238 oC
Furazon
H2O Solubility
210 mg/L (Approximately 50%)
Furazon
State
Solid
Furazon
LogP
0.517
Furazon
Dosage Forms
Ointment
Furazon
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furazon
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furazon
Absorption
Well absorbed.
Furazon
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furazon
Patient Information
No information avaliable
Furazon
Organisms Affected
Gram negative and gram positive bacteria