Furazol
Brand names,
Furazol
Analogs
Furazol
Brand Names Mixture
Furazol
Chemical_Formula
C6H6N4O4
Furazol
RX_link
No information avaliable
Furazol
fda sheet
Furazol
msds (material safety sheet)
Furazol
Synthesis Reference
No information avaliable
Furazol
Molecular Weight
198.136 g/mol
Furazol
Melting Point
238 oC
Furazol
H2O Solubility
210 mg/L (Approximately 50%)
Furazol
State
Solid
Furazol
LogP
0.517
Furazol
Dosage Forms
Ointment
Furazol
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furazol
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furazol
Absorption
Well absorbed.
Furazol
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furazol
Patient Information
No information avaliable
Furazol
Organisms Affected
Gram negative and gram positive bacteria