Furan
Brand names,
Furan
Analogs
Furan
Brand Names Mixture
Furan
Chemical_Formula
C6H6N4O4
Furan
RX_link
No information avaliable
Furan
fda sheet
Furan
msds (material safety sheet)
Furan
Synthesis Reference
No information avaliable
Furan
Molecular Weight
198.136 g/mol
Furan
Melting Point
238 oC
Furan
H2O Solubility
210 mg/L (Approximately 50%)
Furan
State
Solid
Furan
LogP
0.517
Furan
Dosage Forms
Ointment
Furan
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Furan
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Furan
Absorption
Well absorbed.
Furan
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Furan
Patient Information
No information avaliable
Furan
Organisms Affected
Gram negative and gram positive bacteria