Coca
Brand names,
Coca
Analogs
Coca
Brand Names Mixture
Coca
Chemical_Formula
C6H6N4O4
Coca
RX_link
No information avaliable
Coca
fda sheet
Coca
msds (material safety sheet)
Coca
Synthesis Reference
No information avaliable
Coca
Molecular Weight
198.136 g/mol
Coca
Melting Point
238 oC
Coca
H2O Solubility
210 mg/L (Approximately 50%)
Coca
State
Solid
Coca
LogP
0.517
Coca
Dosage Forms
Ointment
Coca
Indication
For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
Coca
Pharmacology
Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.
Coca
Absorption
Well absorbed.
Coca
side effects and Toxicity
Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.
Coca
Patient Information
No information avaliable
Coca
Organisms Affected
Gram negative and gram positive bacteria