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COC Brand names, COC Analogs

COC Brand Names Mixture

  • No information avaliable

COC Chemical_Formula

C6H6N4O4

COC RX_link

No information avaliable

COC fda sheet

COC msds (material safety sheet)

COC MSDS

COC Synthesis Reference

No information avaliable

COC Molecular Weight

198.136 g/mol

COC Melting Point

238 oC

COC H2O Solubility

210 mg/L (Approximately 50%)

COC State

Solid

COC LogP

0.517

COC Dosage Forms

Ointment

COC Indication

For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.

COC Pharmacology

Nitrofurazone is a topical antibacterial agent indicated as an adjunctive therapy for second and third degree burns when resistance to other agents is a real or potential problem. Nitrofurazone is also indicated in skin grafting when bacterial contamination may cause graft rejection or donor site infection, especially in hospitals with a history of resistant bacteria.

COC Absorption

Well absorbed.

COC side effects and Toxicity

Rat LD50 = 590 mg/kg; Allergic contact dermatitis is the most frequently reported adverse effect, occurring in approximately 1 % of patients treated.

COC Patient Information

No information avaliable

COC Organisms Affected

Gram negative and gram positive bacteria