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Thiocid Brand names, Thiocid Analogs

Thiocid Brand Names Mixture

  • No information avaliable

Thiocid Chemical_Formula


Thiocid RX_link

Thiocid fda sheet

Thiocid msds (material safety sheet)

Thiocid MSDS

Thiocid Synthesis Reference

No information avaliable

Thiocid Molecular Weight

296.543 g/mol

Thiocid Melting Point

71.5 oC

Thiocid H2O Solubility

4.09 mg/L

Thiocid State


Thiocid LogP


Thiocid Dosage Forms


Thiocid Indication

For the treatment and management of chronic alcoholism

Thiocid Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Thiocid Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Thiocid side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Thiocid Patient Information

No information avaliable

Thiocid Organisms Affected

Humans and other mammals