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Stopaethyl Brand names, Stopaethyl Analogs

Stopaethyl Brand Names Mixture

  • No information avaliable

Stopaethyl Chemical_Formula


Stopaethyl RX_link

Stopaethyl fda sheet

Stopaethyl msds (material safety sheet)

Stopaethyl MSDS

Stopaethyl Synthesis Reference

No information avaliable

Stopaethyl Molecular Weight

296.543 g/mol

Stopaethyl Melting Point

71.5 oC

Stopaethyl H2O Solubility

4.09 mg/L

Stopaethyl State


Stopaethyl LogP


Stopaethyl Dosage Forms


Stopaethyl Indication

For the treatment and management of chronic alcoholism

Stopaethyl Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Stopaethyl Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Stopaethyl side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Stopaethyl Patient Information

No information avaliable

Stopaethyl Organisms Affected

Humans and other mammals