Ethyl Tuex

Ethyl Tuex Brand names, Ethyl Tuex Analogs

Ethyl Tuex Brand Names Mixture

No information avaliable

Ethyl Tuex Chemical_Formula

C₁₀H₂₀N₂S₄

Ethyl Tuex RX_link

http://www.rxlist.com/cgi/generic/disulfiram.htm

Ethyl Tuex fda sheet

Ethyl Tuex msds (material safety sheet)

Ethyl_Tuex MSDS

Ethyl Tuex Synthesis Reference

No information avaliable

Ethyl Tuex Molecular Weight

296.543 g/mol

Ethyl Tuex Melting Point

71.5 ^oC

Ethyl Tuex H₂O Solubility

4.09 mg/L

Ethyl Tuex State

Solid

Ethyl Tuex LogP

4.422

Ethyl Tuex Dosage Forms

Tablet

Ethyl Tuex Indication

For the treatment and management of chronic alcoholism

Ethyl Tuex Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Ethyl Tuex Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Ethyl Tuex side effects and Toxicity

LD₅₀=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Ethyl Tuex Patient Information