Ekaland Tetd

Ekaland Tetd Brand names, Ekaland Tetd Analogs

Ekaland Tetd Brand Names Mixture

No information avaliable

Ekaland Tetd Chemical_Formula

C₁₀H₂₀N₂S₄

Ekaland Tetd RX_link

http://www.rxlist.com/cgi/generic/disulfiram.htm

Ekaland Tetd fda sheet

Ekaland Tetd msds (material safety sheet)

Ekaland_Tetd MSDS

Ekaland Tetd Synthesis Reference

No information avaliable

Ekaland Tetd Molecular Weight

296.543 g/mol

Ekaland Tetd Melting Point

71.5 ^oC

Ekaland Tetd H₂O Solubility

4.09 mg/L

Ekaland Tetd State

Solid

Ekaland Tetd LogP

4.422

Ekaland Tetd Dosage Forms

Tablet

Ekaland Tetd Indication

For the treatment and management of chronic alcoholism

Ekaland Tetd Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Ekaland Tetd Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Ekaland Tetd side effects and Toxicity

LD₅₀=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Ekaland Tetd Patient Information