Tuads, Ethyl en es it fr

Tuads, Ethyl Brand names, Tuads, Ethyl Analogs

Tuads, Ethyl Brand Names Mixture

  • No information avaliable

Tuads, Ethyl Chemical_Formula


Tuads, Ethyl RX_link


Tuads, Ethyl fda sheet

Tuads, Ethyl msds (material safety sheet)

Tuads,_Ethyl MSDS

Tuads, Ethyl Synthesis Reference

No information avaliable

Tuads, Ethyl Molecular Weight

296.543 g/mol

Tuads, Ethyl Melting Point

71.5 oC

Tuads, Ethyl H2O Solubility

4.09 mg/L

Tuads, Ethyl State


Tuads, Ethyl LogP


Tuads, Ethyl Dosage Forms


Tuads, Ethyl Indication

For the treatment and management of chronic alcoholism

Tuads, Ethyl Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Tuads, Ethyl Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Tuads, Ethyl side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Tuads, Ethyl Patient Information

No information avaliable

Tuads, Ethyl Organisms Affected

Humans and other mammals