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Ethyl Thiurad Brand names, Ethyl Thiurad Analogs

Ethyl Thiurad Brand Names Mixture

  • No information avaliable

Ethyl Thiurad Chemical_Formula


Ethyl Thiurad RX_link

Ethyl Thiurad fda sheet

Ethyl Thiurad msds (material safety sheet)

Ethyl_Thiurad MSDS

Ethyl Thiurad Synthesis Reference

No information avaliable

Ethyl Thiurad Molecular Weight

296.543 g/mol

Ethyl Thiurad Melting Point

71.5 oC

Ethyl Thiurad H2O Solubility

4.09 mg/L

Ethyl Thiurad State


Ethyl Thiurad LogP


Ethyl Thiurad Dosage Forms


Ethyl Thiurad Indication

For the treatment and management of chronic alcoholism

Ethyl Thiurad Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Ethyl Thiurad Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Ethyl Thiurad side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Ethyl Thiurad Patient Information

No information avaliable

Ethyl Thiurad Organisms Affected

Humans and other mammals