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Tenutex Brand names, Tenutex Analogs

Tenutex Brand Names Mixture

  • No information avaliable

Tenutex Chemical_Formula


Tenutex RX_link


Tenutex fda sheet

Tenutex msds (material safety sheet)

Tenutex MSDS

Tenutex Synthesis Reference

No information avaliable

Tenutex Molecular Weight

296.543 g/mol

Tenutex Melting Point

71.5 oC

Tenutex H2O Solubility

4.09 mg/L

Tenutex State


Tenutex LogP


Tenutex Dosage Forms


Tenutex Indication

For the treatment and management of chronic alcoholism

Tenutex Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Tenutex Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Tenutex side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Tenutex Patient Information

No information avaliable

Tenutex Organisms Affected

Humans and other mammals