Ethyl Thiudad en es it fr

Ethyl Thiudad Brand names, Ethyl Thiudad Analogs

Ethyl Thiudad Brand Names Mixture

  • No information avaliable

Ethyl Thiudad Chemical_Formula

C10H20N2S4

Ethyl Thiudad RX_link

http://www.rxlist.com/cgi/generic/disulfiram.htm

Ethyl Thiudad fda sheet

Ethyl Thiudad msds (material safety sheet)

Ethyl_Thiudad MSDS

Ethyl Thiudad Synthesis Reference

No information avaliable

Ethyl Thiudad Molecular Weight

296.543 g/mol

Ethyl Thiudad Melting Point

71.5 oC

Ethyl Thiudad H2O Solubility

4.09 mg/L

Ethyl Thiudad State

Solid

Ethyl Thiudad LogP

4.422

Ethyl Thiudad Dosage Forms

Tablet

Ethyl Thiudad Indication

For the treatment and management of chronic alcoholism

Ethyl Thiudad Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Ethyl Thiudad Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Ethyl Thiudad side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Ethyl Thiudad Patient Information

No information avaliable

Ethyl Thiudad Organisms Affected

Humans and other mammals