Perkacit Tetd en es it fr

Perkacit Tetd Brand names, Perkacit Tetd Analogs

Perkacit Tetd Brand Names Mixture

  • No information avaliable

Perkacit Tetd Chemical_Formula


Perkacit Tetd RX_link

Perkacit Tetd fda sheet

Perkacit Tetd msds (material safety sheet)

Perkacit_Tetd MSDS

Perkacit Tetd Synthesis Reference

No information avaliable

Perkacit Tetd Molecular Weight

296.543 g/mol

Perkacit Tetd Melting Point

71.5 oC

Perkacit Tetd H2O Solubility

4.09 mg/L

Perkacit Tetd State


Perkacit Tetd LogP


Perkacit Tetd Dosage Forms


Perkacit Tetd Indication

For the treatment and management of chronic alcoholism

Perkacit Tetd Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Perkacit Tetd Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Perkacit Tetd side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Perkacit Tetd Patient Information

No information avaliable

Perkacit Tetd Organisms Affected

Humans and other mammals