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Ethyl Thiram Brand names, Ethyl Thiram Analogs

Ethyl Thiram Brand Names Mixture

  • No information avaliable

Ethyl Thiram Chemical_Formula


Ethyl Thiram RX_link

Ethyl Thiram fda sheet

Ethyl Thiram msds (material safety sheet)

Ethyl_Thiram MSDS

Ethyl Thiram Synthesis Reference

No information avaliable

Ethyl Thiram Molecular Weight

296.543 g/mol

Ethyl Thiram Melting Point

71.5 oC

Ethyl Thiram H2O Solubility

4.09 mg/L

Ethyl Thiram State


Ethyl Thiram LogP


Ethyl Thiram Dosage Forms


Ethyl Thiram Indication

For the treatment and management of chronic alcoholism

Ethyl Thiram Pharmacology

Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to hereinafter as the disulfiram-alcohol reaction. This reaction, which is proportional to the dosage of both disulfiram and alcohol, will persist as long as alcohol is being metabolized. Disulfiram does not appear to influence the rate of alcohol elimination from the body. Prolonged administration of disulfiram does not produce tolerance; the longer a patient remains on therapy, the more exquisitely sensitive he becomes to alcohol.

Ethyl Thiram Absorption

Disulfiram is absorbed slowly from the gastrointestinal tract (80 to 90% of oral dose).

Ethyl Thiram side effects and Toxicity

LD50=8.6g/kg (orally in rats). Symptoms of overdose include irritation, slight drowsiness, unpleasant taste, mild GI disturbances, and orthostatic hypotension.

Ethyl Thiram Patient Information

No information avaliable

Ethyl Thiram Organisms Affected

Humans and other mammals