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(Extra Strength) Acetaminophen, Caffeine & 8mg Codeine Phosphate Caplets (Acetaminophen + Caffeine + Codeine Phosphate) 217 (Acetylsalicylic Acid + Caffeine Citrate) 217 Strong Tab (Acetylsalicylic Acid + Caffeine Citrate) 222 Tablet (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate) 282 Mep (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate + Meprobamate) 282 Mep Tab (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate + Meprobamate) 282 Tab (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate) 282 Tablets (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate) 292 Tab (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate) 292 Tablets (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate) 692 Tab (Acetylsalicylic Acid + Caffeine + Dextropropoxyphene Hydrochloride) 692 Tablet (Acetylsalicylic Acid + Caffeine + Dextropropoxyphene Hydrochloride) a & C Tablets with Codeine 15mg (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) a & C Tablets with Codeine 30mg (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) a C and C Tab 0.125gr (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) A.C. & C 8mg Tab (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) A.C.& C Tablets (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Ac and C Tab 1/8gr (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Ac&C Tablets (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Acet 2 (Acetaminophen + Caffeine + Codeine Phosphate) Acet 3 (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen 300 Mg with Caffeine & Codeine Caplet (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen 500mg Cmpd Tab W Codeine (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen Caffeine & 8mg Cod Phos Tab (Acetaminophen + Caffeine + Codeine (Codeine Phosphate)) Acetaminophen Caffeine & 8mg Cod. Phos. Tab (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen Compound Caplets with Codeine (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen Compound Tablets with Codeine (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen Compound Tablets with Codeine 8mg (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen Extra Strength W Caf & Codeine (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen W Caffeine and Codeine (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen W Codeine Tab (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen with Codeine - Caplet (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen, Caffeine & 8mg Codeine Phosphate (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen, Caffeine & 8mg Codeine Phosphate Tablets (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen, Caffeine and 8 Mg of Codeine Phosphate Tablets (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophen, Caffeine, and 8mg of Codeine Phosphate Tablets (Acetaminophen + Caffeine + Codeine Phosphate) Acetaminophene Codeine Et Cafeine Caplets (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Acetaminophene Codeine Et Cafeine Fort (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Acetylsalicylic Acid Caffeine & 8mg Cod Phos (Acetylsalicylic Acid + Caffeine + Codeine (Codeine Phosphate)) Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate Tablets (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Acetylsalicylic Acid, Caffeine and 8mg Codeine Phosphate (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Alka-Seltzer Morning Relief (Acetylsalicylic Acid + Caffeine) Anacin Caplet (Acetylsalicylic Acid + Caffeine) Anacin Caplets (Acetylsalicylic Acid + Caffeine) Anacin Extra Strength Caplet (Acetylsalicylic Acid + Caffeine) Anacin Extra Strength Tablet (Acetylsalicylic Acid + Caffeine) Anacin Tab (Acetylsalicylic Acid + Caffeine) Anacin Tablet (Acetylsalicylic Acid + Caffeine) Anacin with Codeine Tab (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Antidol Tablets (Acetylsalicylic Acid + Caffeine) Arco Pain Tab (Acetylsalicylic Acid + Caffeine Citrate) Asa, Caffeine & 8mg Codeine Phosphate (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Astone Cap (Acetylsalicylic Acid + Caffeine) Atasol 15 Tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Atasol 30 Tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Atasol 8 Tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) C T Acetylsalicylic Acid Codeine and Caf Tab (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) C-2 Buffered with Codeine (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) C2 Buffered Tab (Acetylsalicylic Acid + Aluminum Hydroxide + Caffeine + Magnesium Hydroxide) C2 Buffered with Codeine Tab (Acetylsalicylic Acid + Aluminum Hydroxide + Caffeine + Codeine Phosphate + Magnesium Hydroxide) C2 Tab with Codeine (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Cafergot Pb Sup (Belladonna + Caffeine + Ergotamine (Ergotamine Tartrate) + Pentobarbital) Cafergot Pb Tab (Belladonna + Caffeine + Ergotamine (Ergotamine Tartrate) + Pentobarbital Sodium) Cafergot Sup (Caffeine + Ergotamine Tartrate) Cafergot Tab (Caffeine + Ergotamine Tartrate) Calmine Tab (Acetylsalicylic Acid + Caffeine) Codamin No2 (Acetaminophen + Caffeine + Codeine Phosphate) Codamin No3 (Acetaminophen + Caffeine + Codeine Phosphate) Codaminophen Tab 1/8gr (Acetaminophen + Caffeine + Codeine Phosphate) Corytab (Acetaminophen + Caffeine + Diphenylpyraline Hydrochloride) Cotabs (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Darvon N Compound Pulvule 405 (Acetylsalicylic Acid + Caffeine + Dextropropoxyphene Napsylate) Dolomine 37 (Acetylsalicylic Acid + Caffeine) Dristan Capsules (Acetylsalicylic Acid + Caffeine + Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Emercidin D Tab (Acetaminophen + Caffeine + Diphenylpyraline Hydrochloride + Phenylpropanolamine Hydrochloride) Emertabs Tab (Acetaminophen + Caffeine + Phenylpropanolamine Hydrochloride) Ergodryl Cap (Caffeine Citrate + Diphenhydramine Hydrochloride + Ergotamine Tartrate) Excedrin (Acetaminophen + Caffeine) Excedrin Extra-Strength (Acetaminophen + Caffeine) Excedrin Tab (Acetaminophen + Caffeine) Exdol 15tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Exdol 30tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Exdol 8 Tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Exdol-15 Tablets (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Exdol-30 Tablets (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Exdol-8 Tablets (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Extra Strength Midol (Acetylsalicylic Acid + Caffeine) Fiorinal C1/2 Cap (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate) Fiorinal C1/4 Cap (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate) Fiorinal Cap (Acetylsalicylic Acid + Butalbital + Caffeine) Fiorinal Tab (Acetylsalicylic Acid + Butalbital + Caffeine) Gravergol Capsules (Caffeine + Dimenhydrinate + Ergotamine Tartrate) Herbopyrine Tab 325mg (Acetylsalicylic Acid + Caffeine Citrate) Instantine - Tab (Acetylsalicylic Acid + Caffeine) Instantine - Tablets (Acetylsalicylic Acid + Caffeine) Instantine Tab (Acetylsalicylic Acid + Caffeine) Madelon (Acetylsalicylic Acid + Caffeine) Megral Tabs (Caffeine + Cyclizine Hydrochloride + Ergotamine Tartrate) Midol - Caplet (Acetylsalicylic Acid + Caffeine + Cinnamedrine) Midol Extra Strength Gelcaps (Acetaminophen + Caffeine + Pyrilamine Maleate) Midol Extra Strength Menstrual (Acetaminophen + Caffeine + Pyrilamine Maleate) Midol Menstrual Formula - Caplet (Acetylsalicylic Acid + Caffeine) Midol Multi-Symptom Caplets Extra Strength (Acetaminophen + Caffeine + Pyrilamine Maleate) Midol Multi-Symptom Gelcap Extra Strength (Acetaminophen + Caffeine + Pyrilamine Maleate) Midol Regular (Acetylsalicylic Acid + Caffeine) Midol Tab (Acetylsalicylic Acid + Caffeine + Cinnamedrine) Neo Tigol Tab (Acetylsalicylic Acid + Aluminum Hydroxide + Caffeine + Magnesium Hydroxide + Passion Flower + Valerian) Nervine (Acetylsalicylic Acid + Caffeine) Nervine Tab (Acetylsalicylic Acid + Caffeine) Norgesic Forte Tab (Acetylsalicylic Acid + Caffeine + Orphenadrine Citrate) Norgesic Tab (Acetylsalicylic Acid + Caffeine + Orphenadrine Citrate) Novo Ac and C 8mg Tab (Acetylsalicylic Acid + Caffeine + Codeine Phosphate) Novo-Gesic C15 (Acetaminophen + Caffeine + Codeine Phosphate) Novo-Gesic C30 (Acetaminophen + Caffeine + Codeine Phosphate) Novo-Gesic-C8 (Acetaminophen + Caffeine + Codeine Phosphate) Novo-Propoxyn Compound Cap (Acetylsalicylic Acid + Caffeine + Dextropropoxyphene Hydrochloride) Oradrine 2 Tab (Acetaminophen + Caffeine + Diphenylpyraline Hydrochloride + Phenylpropanolamine Hydrochloride) Oradrine Tablets (Acetaminophen + Caffeine + Codeine Phosphate + Diphenylpyraline Hydrochloride + Phenylpropanolamine Hydrochloride) Oradrine-2 Tab (Acetaminophen + Caffeine + Diphenylpyraline Hydrochloride + Phenylpropanolamine Hydrochloride) Pain Aid (Acetylsalicylic Acid + Caffeine) Painex Tab 0.25gr (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate) Painex Tab 0.5gr (Acetylsalicylic Acid + Caffeine Citrate + Codeine Phosphate) Ratio-Lenoltec No 1 (Acetaminophen + Caffeine + Codeine Phosphate) Ratio-Lenoltec No 2 (Acetaminophen + Caffeine + Codeine Phosphate) Ratio-Lenoltec No 3 (Acetaminophen + Caffeine + Codeine Phosphate) Ratio-Tecnal (Acetylsalicylic Acid + Butalbital + Caffeine) Ratio-Tecnal C 1/2 (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate) Ratio-Tecnal C1/4 (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate) Sinugex 38 (Acetaminophen + Caffeine + Diphenylpyraline Hydrochloride) Triaminicin Colds & Flu Caplets (Acetaminophen + Caffeine + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate) Trianal Capsules (Acetylsalicylic Acid + Butalbital + Caffeine) Trianal Tablet (Acetylsalicylic Acid + Butalbital + Caffeine) Trianal-C 1/2 Capsule (Acetylsalicylic Acid + Butalbital + Caffeine + Codeine Phosphate) Triatec-8 Fort Tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Triatec-8 Tab (Acetaminophen + Caffeine Citrate + Codeine Phosphate) Tylenol No 1 Tab (Acetaminophen + Caffeine + Codeine Phosphate) Tylenol No.1 Caplets (Acetaminophen + Caffeine + Codeine Phosphate) Tylenol No.1 Forte Caplets (Acetaminophen + Caffeine + Codeine Phosphate) Tylenol No1 Forte Tablets with Codeine (Acetaminophen + Caffeine + Codeine Phosphate) Tylenol Ultra Relief (Acetaminophen + Caffeine) Tylenol W Codeine No2 Tab (Acetaminophen + Caffeine + Codeine Phosphate) Tylenol W Codeine No3 Tab (Acetaminophen + Caffeine + Codeine Phosphate) Tylenol with Codeine No. 2 - Tab (Acetaminophen + Caffeine + Codeine Phosphate) Tylenol with Codeine No. 3 - Tab (Acetaminophen + Caffeine + Codeine Phosphate) Ultra Headache Relief (Acetaminophen + Caffeine) Wigraine Suppositories (Belladonna + Caffeine + Ergotamine Tartrate) Wigraine Tab (Belladonna + Caffeine + Ergotamine Tartrate)
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Formula chimica
C8H10N4O2
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RX link
http://www.rxlist.com/cgi/generic3/caffeine.htm
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FDA foglio
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DMS (foglio di materiale di sicurezza)
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Sintesi di riferimento
US Pat. 2,508,545 (1950)
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Peso molecolare
194.191 g/mol
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Temperatura di fusione
238 oC
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H2O Solubilita
22 mg / ml
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Stato
Solid
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LogP
-0.07
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Forme di dosaggio
Capsula; Gocce; liquidi; pillola; Tablet
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Indicazione
Per la gestione della fatica, ipotensione ortostatica, e per il trattamento a breve termine di apnea della prematurità nei neonati.
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Farmacologia
La caffeina, un derivato naturale xantina come teobromina e la teofillina broncodilatatore, è utilizzato come stimolante del SNC, diuretica mite e stimolante respiratorio (nei neonati con apnea di prematurità). Spesso in combinazione con analgesici o con alcaloidi della segale cornuta, la caffeina è usato per curare l'emicrania e altri tipi di mal di testa. Over the counter, la caffeina è disponibile per il trattamento di sonnolenza o ad acqua leggera -Aumento di peso.
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Assorbimento
Prontamente assorbito dopo somministrazione orale o parenterale. Il picco plasmatico per la gamma caffeina da 6-10mg / L e il tempo medio per raggiungere il picco della concentrazione variava da 30 minuti a 2 ore.
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Tossicita
LD50 = 127 mg / kg (per via orale nei topi)
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Informazioni paziente
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Atto interessato organismi
Gli esseri umani e altri mammiferi