Nodaca
Brand names,
Nodaca
Analogs
Nodaca
Brand Names Mixture
Nodaca
Chemical_Formula
C8H10N4O2
Nodaca
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Nodaca
fda sheet
Nodaca
msds (material safety sheet)
Nodaca
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Nodaca
Molecular Weight
194.191 g/mol
Nodaca
Melting Point
238 oC
Nodaca
H2O Solubility
22 mg/ml
Nodaca
State
Solid
Nodaca
LogP
-0.07
Nodaca
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Nodaca
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Nodaca
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Nodaca
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Nodaca
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Nodaca
Patient Information
Nodaca
Organisms Affected
Humans and other mammals