Propoxyphene Compound 65
Brand names,
Propoxyphene Compound 65
Analogs
Propoxyphene Compound 65
Brand Names Mixture
Propoxyphene Compound 65
Chemical_Formula
C8H10N4O2
Propoxyphene Compound 65
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Propoxyphene Compound 65
fda sheet
Propoxyphene Compound 65
msds (material safety sheet)
Propoxyphene Compound 65
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Propoxyphene Compound 65
Molecular Weight
194.191 g/mol
Propoxyphene Compound 65
Melting Point
238 oC
Propoxyphene Compound 65
H2O Solubility
22 mg/ml
Propoxyphene Compound 65
State
Solid
Propoxyphene Compound 65
LogP
-0.07
Propoxyphene Compound 65
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Propoxyphene Compound 65
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Propoxyphene Compound 65
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Propoxyphene Compound 65
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Propoxyphene Compound 65
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Propoxyphene Compound 65
Patient Information
Propoxyphene Compound 65
Organisms Affected
Humans and other mammals