Norgesic Forte
Brand names,
Norgesic Forte
Analogs
Norgesic Forte
Brand Names Mixture
Norgesic Forte
Chemical_Formula
C8H10N4O2
Norgesic Forte
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Norgesic Forte
fda sheet
Norgesic Forte
msds (material safety sheet)
Norgesic Forte
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Norgesic Forte
Molecular Weight
194.191 g/mol
Norgesic Forte
Melting Point
238 oC
Norgesic Forte
H2O Solubility
22 mg/ml
Norgesic Forte
State
Solid
Norgesic Forte
LogP
-0.07
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Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Norgesic Forte
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Norgesic Forte
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Norgesic Forte
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Norgesic Forte
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
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Patient Information
Norgesic Forte
Organisms Affected
Humans and other mammals