Cafamil
Brand names,
Cafamil
Analogs
Cafamil
Brand Names Mixture
Cafamil
Chemical_Formula
C8H10N4O2
Cafamil
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Cafamil
fda sheet
Cafamil
msds (material safety sheet)
Cafamil
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Cafamil
Molecular Weight
194.191 g/mol
Cafamil
Melting Point
238 oC
Cafamil
H2O Solubility
22 mg/ml
Cafamil
State
Solid
Cafamil
LogP
-0.07
Cafamil
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Cafamil
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Cafamil
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Cafamil
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Cafamil
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Cafamil
Patient Information
Cafamil
Organisms Affected
Humans and other mammals