Vivarin
Brand names,
Vivarin
Analogs
Vivarin
Brand Names Mixture
Vivarin
Chemical_Formula
C8H10N4O2
Vivarin
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Vivarin
fda sheet
Vivarin
msds (material safety sheet)
Vivarin
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Vivarin
Molecular Weight
194.191 g/mol
Vivarin
Melting Point
238 oC
Vivarin
H2O Solubility
22 mg/ml
Vivarin
State
Solid
Vivarin
LogP
-0.07
Vivarin
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Vivarin
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Vivarin
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Vivarin
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Vivarin
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Vivarin
Patient Information
Vivarin
Organisms Affected
Humans and other mammals