Phensal
Brand names,
Phensal
Analogs
Phensal
Brand Names Mixture
Phensal
Chemical_Formula
C8H10N4O2
Phensal
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Phensal
fda sheet
Phensal
msds (material safety sheet)
Phensal
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Phensal
Molecular Weight
194.191 g/mol
Phensal
Melting Point
238 oC
Phensal
H2O Solubility
22 mg/ml
Phensal
State
Solid
Phensal
LogP
-0.07
Phensal
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Phensal
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Phensal
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Phensal
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Phensal
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Phensal
Patient Information
Phensal
Organisms Affected
Humans and other mammals