Caffein
Brand names,
Caffein
Analogs
Caffein
Brand Names Mixture
Caffein
Chemical_Formula
C8H10N4O2
Caffein
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Caffein
fda sheet
Caffein
msds (material safety sheet)
Caffein
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Caffein
Molecular Weight
194.191 g/mol
Caffein
Melting Point
238 oC
Caffein
H2O Solubility
22 mg/ml
Caffein
State
Solid
Caffein
LogP
-0.07
Caffein
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Caffein
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Caffein
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Caffein
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Caffein
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Caffein
Patient Information
Caffein
Organisms Affected
Humans and other mammals