Caffedrine Caplets
Brand names,
Caffedrine Caplets
Analogs
Caffedrine Caplets
Brand Names Mixture
Caffedrine Caplets
Chemical_Formula
C8H10N4O2
Caffedrine Caplets
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Caffedrine Caplets
fda sheet
Caffedrine Caplets
msds (material safety sheet)
Caffedrine Caplets
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Caffedrine Caplets
Molecular Weight
194.191 g/mol
Caffedrine Caplets
Melting Point
238 oC
Caffedrine Caplets
H2O Solubility
22 mg/ml
Caffedrine Caplets
State
Solid
Caffedrine Caplets
LogP
-0.07
Caffedrine Caplets
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Caffedrine Caplets
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Caffedrine Caplets
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Caffedrine Caplets
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Caffedrine Caplets
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Caffedrine Caplets
Patient Information
Caffedrine Caplets
Organisms Affected
Humans and other mammals