Miudol
Brand names,
Miudol
Analogs
Miudol
Brand Names Mixture
Miudol
Chemical_Formula
C8H10N4O2
Miudol
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Miudol
fda sheet
Miudol
msds (material safety sheet)
Miudol
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Miudol
Molecular Weight
194.191 g/mol
Miudol
Melting Point
238 oC
Miudol
H2O Solubility
22 mg/ml
Miudol
State
Solid
Miudol
LogP
-0.07
Miudol
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Miudol
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Miudol
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Miudol
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Miudol
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Miudol
Patient Information
Miudol
Organisms Affected
Humans and other mammals