Methyltheobromide
Brand names,
Methyltheobromide
Analogs
Methyltheobromide
Brand Names Mixture
Methyltheobromide
Chemical_Formula
C8H10N4O2
Methyltheobromide
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Methyltheobromide
fda sheet
Methyltheobromide
msds (material safety sheet)
Methyltheobromide
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Methyltheobromide
Molecular Weight
194.191 g/mol
Methyltheobromide
Melting Point
238 oC
Methyltheobromide
H2O Solubility
22 mg/ml
Methyltheobromide
State
Solid
Methyltheobromide
LogP
-0.07
Methyltheobromide
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Methyltheobromide
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Methyltheobromide
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Methyltheobromide
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Methyltheobromide
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Methyltheobromide
Patient Information
Methyltheobromide
Organisms Affected
Humans and other mammals