Methyltheobromine
Brand names,
Methyltheobromine
Analogs
Methyltheobromine
Brand Names Mixture
Methyltheobromine
Chemical_Formula
C8H10N4O2
Methyltheobromine
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Methyltheobromine
fda sheet
Methyltheobromine
msds (material safety sheet)
Methyltheobromine
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Methyltheobromine
Molecular Weight
194.191 g/mol
Methyltheobromine
Melting Point
238 oC
Methyltheobromine
H2O Solubility
22 mg/ml
Methyltheobromine
State
Solid
Methyltheobromine
LogP
-0.07
Methyltheobromine
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Methyltheobromine
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Methyltheobromine
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Methyltheobromine
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Methyltheobromine
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Methyltheobromine
Patient Information
Methyltheobromine
Organisms Affected
Humans and other mammals