Natural Caffeinum
Brand names,
Natural Caffeinum
Analogs
Natural Caffeinum
Brand Names Mixture
Natural Caffeinum
Chemical_Formula
C8H10N4O2
Natural Caffeinum
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Natural Caffeinum
fda sheet
Natural Caffeinum
msds (material safety sheet)
Natural Caffeinum
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Natural Caffeinum
Molecular Weight
194.191 g/mol
Natural Caffeinum
Melting Point
238 oC
Natural Caffeinum
H2O Solubility
22 mg/ml
Natural Caffeinum
State
Solid
Natural Caffeinum
LogP
-0.07
Natural Caffeinum
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Natural Caffeinum
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Natural Caffeinum
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Natural Caffeinum
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Natural Caffeinum
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Natural Caffeinum
Patient Information
Natural Caffeinum
Organisms Affected
Humans and other mammals