Theine
Brand names,
Theine
Analogs
Theine
Brand Names Mixture
Theine
Chemical_Formula
C8H10N4O2
Theine
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Theine
fda sheet
Theine
msds (material safety sheet)
Theine
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Theine
Molecular Weight
194.191 g/mol
Theine
Melting Point
238 oC
Theine
H2O Solubility
22 mg/ml
Theine
State
Solid
Theine
LogP
-0.07
Theine
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Theine
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Theine
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Theine
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Theine
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Theine
Patient Information
Theine
Organisms Affected
Humans and other mammals