Cafcit
Brand names,
Cafcit
Analogs
Cafcit
Brand Names Mixture
Cafcit
Chemical_Formula
C8H10N4O2
Cafcit
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
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fda sheet
Cafcit
msds (material safety sheet)
Cafcit
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Cafcit
Molecular Weight
194.191 g/mol
Cafcit
Melting Point
238 oC
Cafcit
H2O Solubility
22 mg/ml
Cafcit
State
Solid
Cafcit
LogP
-0.07
Cafcit
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Cafcit
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Cafcit
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Cafcit
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Cafcit
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Cafcit
Patient Information
Cafcit
Organisms Affected
Humans and other mammals