Cafeina
Brand names,
Cafeina
Analogs
Cafeina
Brand Names Mixture
Cafeina
Chemical_Formula
C8H10N4O2
Cafeina
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Cafeina
fda sheet
Cafeina
msds (material safety sheet)
Cafeina
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Cafeina
Molecular Weight
194.191 g/mol
Cafeina
Melting Point
238 oC
Cafeina
H2O Solubility
22 mg/ml
Cafeina
State
Solid
Cafeina
LogP
-0.07
Cafeina
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Cafeina
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Cafeina
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Cafeina
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Cafeina
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Cafeina
Patient Information
Cafeina
Organisms Affected
Humans and other mammals