Fiorinal
Brand names,
Fiorinal
Analogs
Fiorinal
Brand Names Mixture
Fiorinal
Chemical_Formula
C8H10N4O2
Fiorinal
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Fiorinal
fda sheet
Fiorinal
msds (material safety sheet)
Fiorinal
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Fiorinal
Molecular Weight
194.191 g/mol
Fiorinal
Melting Point
238 oC
Fiorinal
H2O Solubility
22 mg/ml
Fiorinal
State
Solid
Fiorinal
LogP
-0.07
Fiorinal
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Fiorinal
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Fiorinal
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Fiorinal
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Fiorinal
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Fiorinal
Patient Information
Fiorinal
Organisms Affected
Humans and other mammals