CFF
Brand names,
CFF
Analogs
CFF
Brand Names Mixture
CFF
Chemical_Formula
C8H10N4O2
CFF
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
CFF
fda sheet
CFF
msds (material safety sheet)
CFF
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
CFF
Molecular Weight
194.191 g/mol
CFF
Melting Point
238 oC
CFF
H2O Solubility
22 mg/ml
CFF
State
Solid
CFF
LogP
-0.07
CFF
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
CFF
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
CFF
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
CFF
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
CFF
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
CFF
Patient Information
CFF
Organisms Affected
Humans and other mammals