Propoxyphene Compound-65
Brand names,
Propoxyphene Compound-65
Analogs
Propoxyphene Compound-65
Brand Names Mixture
Propoxyphene Compound-65
Chemical_Formula
C8H10N4O2
Propoxyphene Compound-65
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Propoxyphene Compound-65
fda sheet
Propoxyphene Compound-65
msds (material safety sheet)
Propoxyphene Compound-65
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Propoxyphene Compound-65
Molecular Weight
194.191 g/mol
Propoxyphene Compound-65
Melting Point
238 oC
Propoxyphene Compound-65
H2O Solubility
22 mg/ml
Propoxyphene Compound-65
State
Solid
Propoxyphene Compound-65
LogP
-0.07
Propoxyphene Compound-65
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Propoxyphene Compound-65
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Propoxyphene Compound-65
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Propoxyphene Compound-65
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Propoxyphene Compound-65
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Propoxyphene Compound-65
Patient Information
Propoxyphene Compound-65
Organisms Affected
Humans and other mammals