Theophylline ME
Brand names,
Theophylline ME
Analogs
Theophylline ME
Brand Names Mixture
Theophylline ME
Chemical_Formula
C8H10N4O2
Theophylline ME
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Theophylline ME
fda sheet
Theophylline ME
msds (material safety sheet)
Theophylline ME
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Theophylline ME
Molecular Weight
194.191 g/mol
Theophylline ME
Melting Point
238 oC
Theophylline ME
H2O Solubility
22 mg/ml
Theophylline ME
State
Solid
Theophylline ME
LogP
-0.07
Theophylline ME
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Theophylline ME
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Theophylline ME
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Theophylline ME
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Theophylline ME
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Theophylline ME
Patient Information
Theophylline ME
Organisms Affected
Humans and other mammals